iS Clinical

Science-Led Skincare with iS Clinical

iS Clinical is a leading brand in pharmaceutical-grade skincare, known for its results-driven, multifunctional formulas that support everything from ageing and acne to post-procedure recovery and sensitive skin.

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IS Clinical smoothing essentials set with blue and white packaging on a white backgroundiS Clinical Smoothing Essentials
IS Clinical Balance and Hydrate Duo set with blue bottles and a white box on a white backgroundiS Clinical Balance and Hydrate Duo
iS Clinical Daily Dynamic HydratoriS Clinical Daily Dynamic Hydrator
iS Clinical Rejuvenate & Resurface Regime
iS Clinical Cleansing Complex 180mliS Clinical Cleansing Complex 180ml
iS Clinical Cleansing Complex 180ml

This clear, lightweight cleansing gel is powerful yet gentle enough for hypersensitive skin. Formulated with a balance of bio nutrients, antioxidants and mild resurfacing ingredients that thoroughly cleanse without stripping essential natural oils.

€33,95
iS Clinical Youth Eye ComplexiS Clinical Youth Eye Complex
iS Clinical Youth Eye Complex

This breakthrough formula combines a potent blend of proteins, peptides, growth factors and antioxidants to transform tired, ageing skin around the eyes.

€80,95
iS Clinical Pro-Heal Serum Advance+ 30mliS Clinical Pro-Heal Serum Advance+ 30ml
iS Clinical Pro-Heal Serum Advance+ 30ml

This time-released Vitamin C serum with olive leaf extract and pure Vitamins A and E, helps to provide the skin with antioxidant protection and exceptional healing properties. Ideal for rosacea and acne sufferers as well...

€108,95
iS Clinical Reparative Moisture EmulsioniS Clinical Reparative Moisture Emulsion
iS Clinical Reparative Moisture Emulsion

This innovative daily moisturiser combines pharmaceutical grade botanicals, peptides and powerful antioxidants to deliver multiple anti ageing benefits for a smoother, firmer and more youthful-looking complexion.

€73,95
iS Clinical Active Serum 30mliS Clinical Active Serum 30ml
iS Clinical Active Serum 30ml

A fast acting, results-orientated formula that offers a multitude of benefits with long-term results.

€98,95
iS Clinical Hydra Cool Serum 30mliS Clinical Hydra Cool Serum 30ml
iS Clinical Hydra Cool Serum 30ml

Helping to cool, calm and soothe dry and irritated skin, this serum is formulated with a unique combination of active ingredients to provide both instant and long-term results for compromised skin.

€69,95
iS Clinical Super Serum Advance+ 30mliS Clinical Super Serum Advance+ 30ml
iS Clinical Super Serum Advance+ 30ml

This clinically proven formula contains a unique blend of powerful botanical antioxidants helping to lighten and correct hyperpigmentation, reduce the appearance of fine lines and wrinkles and promote wound healing.

€109,95
iS Clinical Active Peel SystemiS Clinical Active Peel System
iS Clinical Active Peel System

€64,95
iS Clinical Sheald Recovery Balm 60giS Clinical Sheald Recovery Balm 60g
iS Clinical Sheald Recovery Balm 60g

Encourage skin’s natural healing process and alleviate skin irritations with a combination of Ceramides and Oat Kernel Extract. Sheald Recovery Balm can be used following abrasive in-clinic procedures such as laser, microdermabrasion and chemical treatments.

€55,95
iS Clinical Pro-Heal Serum Advance+ 15mliS Clinical Pro-Heal Serum Advance+ 15ml
iS Clinical Pro-Heal Serum Advance+ 15ml

This time-released Vitamin C serum with olive leaf extract and pure Vitamins A and E, helps to provide the skin with antioxidant protection and exceptional healing properties. Ideal for rosacea and acne sufferers as well...

€63,95
iS Clinical Moisturizing ComplexiS Clinical Moisturizing Complex
iS Clinical Moisturizing Complex

This versatile rich, yet easily absorbed moisturiser contains a botanical complex, delivering an antioxidant rich barrier that seals in moisture and insulates skin from external aggressors.

€68,95
iS Clinical Active Serum 15ml vialiS Clinical Active Serum 15ml
iS Clinical Active Serum 15ml

A fast acting, results-orientated formula that offers a multitude of benefits with long-term results.

€61,95
iS Clinical Brightening Serum 30mliS Clinical Brightening Serum 30ml
iS Clinical Brightening Serum 30ml

This lightweight and concentrated serum safely brightens skin with a hydroquinone-free and paraben-free formula that gently resurfaces skin and provides long-term visible improvements.

€96,95
iS Clinical Youth Complex 30giS Clinical Youth Complex 30g
iS Clinical Youth Complex 30g

Clinically proven to stimulate collagen and elastin synthesis, this complex formula enriched with Hyaluronic Acid, Mixed Fruit Acids, Copper Tripeptide and Vitamin B5 offers immediate and long-term results in firming and tightening skin.

€110,95

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iS Clinical Youth Intensive Creme 100ml with the lid removediS Clinical Youth Intensive Creme 100ml
iS Clinical Youth Intensive Creme 100ml

Formulated with iS Clinical’s purest and most effective botanically derived hydrators, antioxidants, resurfacing acids and growth factors, this luxuriously rich anti-ageing moisturiser provides deep hydration as well as visibly reducing the appearance of fine lines...

€268,95
iS Clinical Brightening Complex 30ml
iS Clinical Brightening Complex 30ml

Featuring an innovative blend of proprietary and safe brightening ingredients, alongside pharmaceutical grade botanicals, this unique formula safely and effectively treats hyperpigmentation whilst also hydrating and delivering antioxidant benefits to skin. 

€105,95
iS Clinical Retinol + Emulsion 0.3iS Clinical Retinol + Emulsion 0.3
iS Clinical Warming Honey CleanseriS Clinical Warming Honey Cleanser
iS Clinical Warming Honey Cleanser

Formulated with the purest raw honey, royal jelly, this rich and luxurious cleanser warms upon application to cleanse and gently exfoliate skin, whilst also ensuring skin remains soft, smooth and hydrated. 

€33,95
iS Clinical Extreme Protect SPF 40iS Clinical Extreme Protect SPF 40
iS Clinical Extreme Protect SPF 40

Formulated with antioxidant-rich ingredients and state-of-the-art broad spectrum all-physical sunscreen actives, iS Clinical Extreme Protect SPF 40 supports optimal skin health as it moisturises and protects skin.

€59,95
iS Clinical Super Serum Advance+ 15mliS Clinical Super Serum Advance+ 15ml
iS Clinical Super Serum Advance+ 15ml

This clinically proven formula contains a unique blend of powerful botanical antioxidants helping to lighten and correct hyperpigmentation, reduce the appearance of fine lines and wrinkles and promote wound healing.

€66,95
iS Clinical GenexC Serum 30ml
iS Clinical GenexC Serum 30ml

Support healthy skin with a combination of 20% Vitamin C, fruit acid extracts and natural enzyme, Superoxide Dismutase, to support healthy skin, combat signs of ageing, brighten and improve skin tone and elasticity.

€118,95
iS Clinical Youth Intensive CremeiS Clinical Youth Intensive Creme
iS Clinical Youth Intensive Creme

Formulated with iS Clinical’s purest and most effective botanically derived hydrators, antioxidants, resurfacing acids and growth factors, this luxuriously rich anti-ageing moisturiser provides deep hydration as well as visibly reducing the appearance of fine lines...

€163,95
iS Clinical Cream Cleanser 120mliS Clinical Cream Cleanser 120ml
iS Clinical Cream Cleanser 120ml

This lightweight and hydrating cleansing cream is powerful yet non-irritating in a rich and comforting formula that deeply cleanses whilst strengthening skin’s natural barrier function. The perfect cleanser for sensitive skin.

€33,95
iS Clinical Hydra Intensive Cooling MasqueiS Clinical Hydra Intensive Cooling Masque
iS Clinical Hydra Intensive Cooling Masque

Restore and revitalise sensitive, dehydrated and irritated skin with this soothing and hydrating mask formulated with Hyaluronic Acid, Green Tea, Aloe Vera, Rosemary Leaf Oil and powerful antioxidant, Resveratrol.

€66,95
iS Clinical C Eye Advance+
iS Clinical C Eye Advance+

Specifically formulated to reduce the signs of fatigue and premature ageing around the eye area, this unique formula contains a blend of active ingredients to provide instant and long-term results.

€45,95
iS Clinical Copper Firming Mist 75mliS Clinical Copper Firming Mist 75ml
iS Clinical Copper Firming Mist 75ml

This light, refreshing mist is packed with hydrating and soothing ingredients that transform dull, dehydrated skin into a glowing and radiant complexion.

€28,95
iS Clinical Hydra Cool Serum 15mliS Clinical Hydra Cool Serum 15ml
iS Clinical Hydra Cool Serum 15ml

Helping to cool, calm and soothe dry and irritated skin, this serum is formulated with a unique combination of active ingredients to provide both instant and long-term results for compromised skin.

€44,95
iS Clinical Youth SerumiS Clinical Youth Serum
iS Clinical Youth Serum

Helping to achieve a more youthful and vibrant complexion, iS Clinical Youth Serum contains a unique blend of active ingredients to provide both short-term and long-term results in rebuilding lost collagen, reducing fine lines and...

€110,95
iS Clinical Cleansing Complex Travel Size 60mliS Clinical Cleansing Complex Travel Size 60ml
iS Clinical Cleansing Complex Travel Size 60ml

This clear, lightweight cleansing gel is powerful yet gentle enough for hypersensitive skin. Formulated with a balance of bio nutrients, antioxidants and mild resurfacing ingredients that thoroughly cleanse without stripping essential natural oils.

€17,95
iS Clinical Extreme Protect SPF 40 PerfecTint BeigeiS Clinical Extreme Protect SPF 40 PerfecTint Beige
iS Clinical Extreme Protect SPF 40 PerfecTint Beige

Formulated with antioxidant-rich ingredients and state-of-the-art broad spectrum all-physical sunscreen actives, iS Clinical Extreme Protect SPF 40 PerfecTint Beige supports optimal skin health as it moisturises, protects skin and delivers a subtle tint.

€59,95
iS Clinical NeckPerfect ComplexiS Clinical NeckPerfect Complex
iS Clinical NeckPerfect Complex

This powerful anti-ageing cream tightens, smoothes and sculpts thin, sagging and crepey skin on the neck and décolleté.

€77,95

iS Clinical Skincare

About iS Clinical

Discover the Best of iS Clinical Skincare

iS Clinical brings together botanical actives and clinical technology to deliver high-performance skincare trusted by professionals. Whether you're managing acne, sensitivity, pigmentation or ageing concerns, this range offers targeted solutions that are gentle yet visibly effective.

Find Your Ideal iS Clinical Routine

Explore our curated selection of iS Clinical favourites, including the bestselling Active Serum, the versatile Cleansing Complex, and post-procedure heroes like Sheald Recovery Balm. These multifunctional products help restore clarity, calm inflammation and support healthy, radiant skin.

Advice on Our iS Clinical Range

Need help choosing the right formula? Contact our skincare experts for personalised guidance, visit our blogs to learn more about building a complete iS Clinical routine, or take our free online skin test to discover the best products for your skin type and goals.

Purify and Prep with iS Clinical Cleansers

iS Clinical cleansers are expertly formulated to deliver a deep yet gentle cleanse, making them ideal for all skin types, including sensitive or acne-prone skin. The cult-favourite Cleansing Complex blends botanical extracts with clinical-grade actives to remove excess oil, impurities and makeup without stripping the skin. Perfect as the first step in a results-led routine, these formulas help clarify, soothe and prepare your skin for treatment.

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Expert Sun Protection with iS Clinical

iS Clinical sunscreens offer advanced broad-spectrum protection in elegant, breathable formulas suitable for all skin types, including sensitive and post-treatment skin. With options like Eclipse SPF and Extreme Protect SPF, these sunscreens shield against UVA and UVB damage while supporting the skin barrier with antioxidants and soothing actives. Ideal for daily use, they leave a smooth, non-greasy finish that layers perfectly under makeup or serums.

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Expert Tip for iS Clinical

"Start with the Cleansing Complex to gently purify your skin without disrupting its natural barrier. Follow with a serum like Active Serum or Pro-Heal Serum Advance+ to target specific concerns such as breakouts or dullness. During the day, apply a hydrating product like Hydra-Cool Serum before SPF. At night, layer on a restorative formula such as Sheald Recovery Balm or Reparative Moisture Emulsion. These results-driven steps work together to visibly improve skin clarity, resilience and overall health."

- Kimberley, Clinic & Customer Experience Manager

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iS Clinical: Best-Selling Products and Why Its A Skincare Favourite

When it comes to skincare that genuinely works, iS Clinical is one of the brands we trust most. Loved by facialists, dermatologists and beauty editors, it’s a name you’ll hear a lot in professional skincare.

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Cutting-Edge, Multi-Functional Skincare with iS Clinical

iS Clinical delivers advanced, clinical grade formulas that are botanically derived, multi tasking and results driven. These pharmaceutical grade products, trusted by A list professionals, are pregnancy safe* and feature active ingredients at therapeutic levels. Backed by clinical trials, they deliver visible results you can rely on. Whether you are targeting clarity, firmness or post procedure recovery, iS Clinical combines laboratory performance with natural sophistication.

*As with any treatment we would recommend consulting with your physician before using iS Clinical products if you are pregnant, planning to become pregnant, ornursing.

Frequently Asked Questions

What is iS Clinical best known for?

iS Clinical is best known for its clinically proven formulations, supported by rigorous clinical trials and professional testing. The brand’s results-driven approach and extensive research have made products like the Active Serum, Cleansing Complex and Pro-Heal Serum Advance+ highly respected by dermatologists, aestheticians and skincare professionals worldwide.

Is iS Clinical suitable for sensitive skin?

Yes. Many iS Clinical products, including the Hydra-Cool Serum and Sheald Recovery Balm, are specifically formulated to calm and support reactive, sensitive or post-treatment skin.

What skin concerns does iS Clinical address?

iS Clinical products are designed to tackle acne, ageing, dehydration, hyperpigmentation and skin barrier issues, all within multifunctional formulas.

Can iS Clinical be used after aesthetic procedures?

Yes. iS Clinical is trusted by dermatologists and clinics worldwide for post-procedure care, helping to soothe, hydrate and protect the skin after treatments such as peels, laser or micro-needling.

What makes the Active Serum so popular?

The Active Serum is known for its ability to reduce the appearance of breakouts, fine lines and discolouration, all in one formula. It provides visible results quickly and is suitable for many skin types.

Does iS Clinical use natural or botanical ingredients?

Yes, many of its products contain botanically derived actives, such as sugar cane extract, bilberry, white willow bark and olive leaf, combined with clinically proven actives like salicylic acid and vitamin C.

Can I use iS Clinical products during pregnancy?

Several iS Clinical products are non-systemic and considered safe during pregnancy, but it’s always best to consult your doctor or aesthetic practitioner before starting any new skincare routine.

Is iS Clinical cruelty free?

Yes. iS Clinical does not test on animals and many of its products are vegan-friendly.

How often should I use iS Clinical serums?

Most serums, including the Active Serum and Pro-Heal Serum Advance+, are designed for daily use and can be incorporated into both morning and evening routines.

What’s the difference between Active Serum and Super Serum Advance+?

Active Serum focuses on blemishes, tone and texture, while Super Serum Advance+ combines vitamin C with growth factors for brightening and skin firmness.

Is iS Clinical suitable for all skin types and ages?

Yes. iS Clinical products are formulated to be safe and effective for a wide range of skin types, from sensitive and acne-prone to mature and dry skin. Their gentle yet high-performance botanical ingredients and clinical-grade actives make them suitable for younger skin looking to prevent concerns, as well as more mature skin seeking to address visible signs of ageing.

Achieve A Brighter Complexion With iS Clinical

Join us and iS Clinical educator, Be Loasby Smith, as we discover how iS Clinical's formulations can transform lacklustre, sleepy skin to help you achieve a brighter, more youthful-looking complexion - no matter the season!